Human choline dehydrogenase: Medical promises and biochemical challenges

Medical Education and Human Cloning Challenges

Introduction: Cloning technology has been strengthened a long human desire for eternal life. The possibility of human cloning is the new challenges in medical education and medical ethics. The present study discussed the different perspectives in this field. Methods: This study is a review article. Related books and some database such as SID, Irandoc, Elsevier, PubMed, Magiran were searched us...

Epigenetics of human melanoma: promises and challenges.

Melanoma is the deadliest form of skin cancer with rising incidence and mortality rates. Although early-stage melanoma is highly curable, advanced-stage melanoma is refractory to treatment. This underscores the importance of prevention and early detection as well as the need to improve treatment and prognostication of human melanoma. Elucidating the underlying mechanisms of the initiation and p...

De Novo Human Cardiac Myocytes for Medical Research: Promises and Challenges

The advent of cellular reprogramming technology has revolutionized biomedical research. De novo human cardiac myocytes can now be obtained from direct reprogramming of somatic cells (such as fibroblasts), from induced pluripotent stem cells (iPSCs, which are reprogrammed from somatic cells), and from human embryonic stem cells (hESCs). Such de novo human cardiac myocytes hold great promise for ...

Electronic medical records--promises, promises!

Genetic Variation of Choline Dehydrogenase Gene in Idiopathic Male Infertility

Infertility can be caused by an unexplained reduction in semen quality in males who present asnormal on physical examination and endocrine testing. There is some evidence that aberrantmetabolism of micronutrients such as choline may play a causative role in male factorinfertility. Choline is a crucial factor in the regulation of sperm membrane structure andmotility, and this nutrient plays an i...